Since the closing of St. Louis Centre in 2006, downtown has been without a Walgreens. It once had two, the other being in the ground floor of the Century Building. As a downtown office worker, it was incredibly convenient to be able to pick up necessities or prescriptions just a short walk from the office.
An article in today's Business Journal outlines Walgreens' plans for growth in the St. Louis area and mentions that those plans do not include a downtown store.
My question is, why? With a growing residential population and relatively strong daytime and conventioneer/tourist populations, it makes perfect sense. While not necessarily an "exciting" or "upscale" retailer, Walgreens is the retailer that downtown needs the most.